Cadmium is an important industrial and environmental pollutants, mainly from zinc, copper, lead smelting ore, electroplating, batteries, alloys, paints and plastics and other industrial production. The main source of cadmium contamination in occupational populations is inhalation, and the main sources of cadmium contamination in non-occupational populations are food and inhalation. Cadmium is a non-essential and toxic element of the human body, or a IA-class carcinogen, which is carcinogenic, teratogenic and mutagenic. Especially after the researchers proposed the causal relationship between cadmium pollution and Japanese “pain†in the 1960s, The relationship between environmental cadmium pollution and public health has received increasing attention. Studies have shown that wastewater, waste gas and waste residue from industrial plants and mines are discharged into the environment, causing environmental cadmium pollution, so that the cadmium content of rice and other crops planted by local residents exceeds the standard. The residents consume cadmium-contaminated food and vegetables for a long time, resulting in cadmium load in the body. Gradually increasing, the biological half-life of cadmium in the body is as long as 10-30 years, which is the most known toxic substance that accumulates in the body. The continuous accumulation of cadmium can cause various lesions in the contact. Acute or prolonged inhalation of cadmium-containing soot can cause lung inflammation, bronchitis, emphysema, pulmonary fibrosis, and even lung cancer. Long-term, low-dose exposure to cadmium pollution mainly produces renal lesions with proximal convoluted tubule injury, which is characterized by decreased renal tubular absorption and increased low-molecular protein content in urine. When cadmium is poisoned, the absorption rate of calcium and phosphorus in the kidney is decreased, and the metabolism of vitamin D is abnormal. In the long run, osteoporosis or bone softening may occur in cadmium contacts. Cadmium can also cause tumors in the lungs, prostate, and testes. In the 1960s, there was a strange disease in Toyama Prefecture, Japan. Patients showed painful bone fracture or bending deformation. Most of the patients were menopausal women. Male patients were rare, and they were confined to the irrigation zone of the Shentongchuan Basin. The locals moved to the field. Then it does not happen. The first clinical manifestations are back pain, back pain, knee pain, and later throughout the body. When the pain activity is aggravated, pathological fractures often occur, which causes the body to shorten, and the heavy ones stay in bed for a long time, calling for pain in the day and night, hence the name "pain." Most patients have symptoms of anemia. The etiology of this disease is unknown. A large number of epidemiological investigations have confirmed that "pain" is caused by chronic cadmium poisoning. The cadmium content in local soil and drinking water is significantly higher than other areas, and the cadmium load in patients is much higher than that. normal range. The “painful disease†was identified as one of the four major public nuisances in Japan, and the government and enterprises paid huge economic losses for the treatment and compensation of patients. There are also several typical environmental cadmium pollution areas in China, which have attracted people's attention. For example, the cadmium-pollution area of ​​the Hezhang lead-zinc mine in Guizhou, the cadmium-pollution area in the Zhangshi Irrigation District in Jiangxi, Zhejiang, Wenzhou, and the Zhangshi Irrigation District in Shenyang, etc., the environmental cadmium pollution in these areas is due to private mining of mining and metallurgical resources, or due to cadmium-containing sewage. Unorganized emissions. According to preliminary investigations by environmental epidemiologists, the cadmium content of rice, vegetables and other crops in some areas is seriously exceeding the standard. The cadmium intake of the exposed population through various channels reaches 536.52μg/day/person, far exceeding the national average. -46 μg / day / person, WHO recommended limit of 57-71 μg / day / person, and the Japanese "pain" area intake is 267-353 μg / day / person. According to the survey, some individuals with cadmium-contaminated areas have already experienced chronic early health hazards caused by cadmium pollution, and even patients with suspected “painful illness†have appeared. Because there is no specific treatment for "pain and pain", it is mainly symptomatic treatment. The patient is extremely painful after the onset of illness, and loses the ability to live and has a poor prognosis. Therefore, in order to prevent problems, prevention of the disease and early treatment is the first. Once the environment is contaminated with cadmium, it is very difficult to remove it. Therefore, eliminating the source of pollution and preventing environmental pollution is the most fundamental measure to prevent the disease. 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